Structure of PDB 6y5e Chain F Binding Site BS01

Receptor Information
>6y5e Chain F (length=83) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDA
VTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Ligand information
>6y5e Chain I (length=153) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
atcctggagaatcccggtgccgaggccgctcaattggtcgtagacagctc
tagcaccgcttaaacgcacgtacgcgctgtcccccgcgttttaaccgcca
aggggattactccctagtctccaggcacgtgtcagatatatacatcctgt
gat
Receptor-Ligand Complex Structure
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PDB6y5e Structural mechanism of cGAS inhibition by the nucleosome.
Resolution3.15 Å
Binding residue
(original residue number in PDB)		R46 I47 G49 K80 T81
Binding residue
(residue number reindexed from 1)		R26 I27 G29 K60 T61
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity

View graph for
Molecular Function
External links
PDB RCSB:6y5e, PDBe:6y5e, PDBj:6y5e
PDBsum6y5e
PubMed32911482
UniProtP62805|H4_HUMAN Histone H4 (Gene Name=H4C1)

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