Structure of PDB 6vqx Chain F Binding Site BS01

Receptor Information
>6vqx Chain F (length=334) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ILSTASVLAFERKLDPSDALMSAGAWAQRDASQEWPAVTVREKSVRGTIS
NRLKTKDRDPAKLDASIQSPNLQTVDVANLPSDADTLKVRFTLRVLGGAG
TPSACNDAAYRDKLLQTVATYVNDQGFAELARRYAHNLANARFLWRNRVG
AEAVEVRINHIRQGEVARAWRFDALAIGLRDFKADAELDALAELIASGLS
GSGHVLLEVVAFARIGDGQEVFPSQELILDKGDKKGQKSKTLYSVRDAAA
IHSQKIGNALRTIDTWYPDEDGLGPIAVEPYGSVTSQGKAYRQPKQKLDF
YTLLDNWVLRDEAPAVEQQHYVIANLIRGGVFGE
Ligand information
>6vqx Chain K (length=60) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cuaagaaauucacggcgggcuugauguccgcgucuaccugguucacugcc
guauaggcag
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Receptor-Ligand Complex Structure
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PDB6vqx Inhibition mechanisms of AcrF9, AcrF8, and AcrF6 against type I-F CRISPR-Cas complex revealed by cryo-EM.
Resolution3.15 Å
Binding residue
(original residue number in PDB)		R34 V67 R68 L94 W167 R168 F244 Q247 E248 L249 H274 Q276 K277 N280 T307 S308 R350 G352 V353
Binding residue
(residue number reindexed from 1)		R12 V45 R46 L72 W145 R146 F222 Q225 E226 L227 H252 Q254 K255 N258 T285 S286 R328 G330 V331
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
Biological Process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:6vqx, PDBe:6vqx, PDBj:6vqx
PDBsum6vqx
PubMed32170016
UniProtQ02MM1|CSY3_PSEAB CRISPR-associated protein Csy3 (Gene Name=csy3)

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