Structure of PDB 6u8k Chain F Binding Site BS01
Receptor Information
>6u8k Chain F (length=222) Species:
9606
(Homo sapiens) [
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EVQLVESGGGLVQPGGSLRLSCAASGFYISYSSIHWVRQAPGKGLEWVAS
ISPSSGSTYYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCARSR
YSRYRRGFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLV
KDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQ
TYICNVNHKPSNTKVDKKVEPK
Ligand information
>6u8k Chain B (length=68) [
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gggucucgcggaaccggugaguacaccggaauccaggaaacuggauuugg
gcgugcccccgcgagacc
.<<<<<<<<<<..<<<<<<....>>>>>><<<<<<<....>>>>>>>.<<
<<..>>>>>>>>>>>>>>
Receptor-Ligand Complex Structure
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PDB
6u8k
Synthetic Antibody Binding to a Preorganized RNA Domain of Hepatitis C Virus Internal Ribosome Entry Site Inhibits Translation.
Resolution
2.75 Å
Binding residue
(original residue number in PDB)
R22 Q85
Binding residue
(residue number reindexed from 1)
R19 Q82
Binding affinity
PDBbind-CN
: Kd=37nM
External links
PDB
RCSB:6u8k
,
PDBe:6u8k
,
PDBj:6u8k
PDBsum
6u8k
PubMed
31765566
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