Structure of PDB 6s7o Chain F Binding Site BS01

Receptor Information
>6s7o Chain F (length=241) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KISTEVGITNVDLSTVDKPKTTRVTYPAKAKGTFIAFALFFQLVDVNTGA
ELTPHQTFVRLHNQKTGQEVVFVAEPDNKNVYKFELDTSERKIEFDSASG
TYTLYLIIGDATLKNPILWNVADVVIKFPNLFTPKQEIQHLFREPEKRPP
TVVSNTFTALILSPLLLLFALWIRIGANVSNFTFAPSTIIFHLGHAAMLG
LMYVYWTQLNMFQTLKYLAILGSVTFLAGNRMLAQQAVKRT
Ligand information
Ligand IDMAN
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5+,6+/m1/s1
InChIKeyWQZGKKKJIJFFOK-PQMKYFCFSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(C1C(C(C(C(O1)O)O)O)O)O
CACTVS 3.341OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
CACTVS 3.341OC[C@H]1O[C@H](O)[C@@H](O)[C@@H](O)[C@@H]1O
OpenEye OEToolkits 1.5.0C([C@@H]1[C@H]([C@@H]([C@@H]([C@H](O1)O)O)O)O)O
ACDLabs 10.04OC1C(O)C(OC(O)C1O)CO
FormulaC6 H12 O6
Namealpha-D-mannopyranose;
alpha-D-mannose;
D-mannose;
mannose
ChEMBLCHEMBL365590
DrugBank
ZINCZINC000003860903
PDB chain6s7o Chain J Residue 5 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6s7o Cryo-electron microscopy structures of human oligosaccharyltransferase complexes OST-A and OST-B.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		Q527 H528
Binding residue
(residue number reindexed from 1)		Q139 H140
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006487 protein N-linked glycosylation
Cellular Component
GO:0008250 oligosaccharyltransferase complex
GO:0016020 membrane

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Biological Process
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Cellular Component
External links
PDB RCSB:6s7o, PDBe:6s7o, PDBj:6s7o
PDBsum6s7o
PubMed31831667
UniProtP04844|RPN2_HUMAN Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (Gene Name=RPN2)

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