Structure of PDB 6rwl Chain F Binding Site BS01
Receptor Information
>6rwl Chain F (length=69) Species:
11723
(Simian immunodeficiency virus) [
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IIASDLQTTKLQNQISKIQNFRVYFREGRDQQWKGPATLIWKGEGAVVIQ
DGQDLKVVPRRKCKIIKDY
Ligand information
>6rwl Chain S (length=23) [
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aactggtagagatttttcttagc
Receptor-Ligand Complex Structure
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PDB
6rwl
Structural basis of second-generation HIV integrase inhibitor action and viral resistance.
Resolution
3.36 Å
Binding residue
(original residue number in PDB)
W243 E246 V250 R263
Binding residue
(residue number reindexed from 1)
W41 E44 V48 R61
Enzymatic activity
Enzyme Commision number
3.1.13.2
: exoribonuclease H.
3.1.26.13
: retroviral ribonuclease H.
Gene Ontology
Molecular Function
GO:0003676
nucleic acid binding
GO:0008270
zinc ion binding
Biological Process
GO:0015074
DNA integration
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Molecular Function
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Biological Process
External links
PDB
RCSB:6rwl
,
PDBe:6rwl
,
PDBj:6rwl
PDBsum
6rwl
PubMed
32001525
UniProt
E1ANT8
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