Structure of PDB 6rpb Chain F Binding Site BS01

Receptor Information
>6rpb Chain F (length=274) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFFTSVSRPGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWI
EQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYGCD
VGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAAHV
AEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLR
CWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSG
QEQRYTCHVQHEGLPKPLTLRWEP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6rpb TCRs with Distinct Specificity Profiles Use Different Binding Modes to Engage an Identical Peptide-HLA Complex.
Resolution2.5 Å
Binding residue
(original residue number in PDB)
Y7 M45 E63 K66 V67 H70 T73 V76 D77 T80 Y84 Y99 Y116 T143 K146 W147 V152 L156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 M43 E61 K64 V65 H68 T71 V74 D75 T78 Y82 Y97 Y114 T141 K144 W145 V150 L154 Y157 W165 Y169
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:6rpb, PDBe:6rpb, PDBj:6rpb
PDBsum6rpb
PubMed32102902
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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