Structure of PDB 6pb6 Chain F Binding Site BS01

Receptor Information
>6pb6 Chain F (length=483) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RTTDPVRMYMREMGTVELLTREGEIDIAKRIEDGINQVQCSVAEYPEAIT
YLLEQYDRVEAEEARLSDLITGFVDPNAENSIDPELAREKFAELRAQYVV
TRDTIKAKGRSHATAQEEILKLSEVFKQFRLVPKQFDYLVNSMRVMMDRV
RTQERLIMKLCVEQCKMPKKNFITLFTGNETSDTWFNAAIAMNKPWSEKL
HDVSEEVHRALQKLQQIEEETGLTIEQVKDINRRMSIGEAKARRAKKEMV
EANLRLVISIAKKYTNRGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTY
ATWWIRQAITRSIADQARTIRIPVHMIETINKLNRISRQMLQEMGREPTP
EELAERMLMPEDKIRKVLKIAKEPISMETPIGDDEDSHLGDFIEDTTLEL
PLDSATTESLRAATHDVLAGLTAREAKVLRMRFGIDMNTDYTLEEVGKQF
DVTRERIRQIEAKALRKLRHPSRSEVLRSFLDD
Ligand information
>6pb6 Chain 1 (length=78) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cttttttgcctaaaatgtgatctagatcacatttttcgcatcttttttat
gctataatgtgtgcagtctgacgcggcg
Receptor-Ligand Complex Structure
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PDB6pb6 Visualization of two architectures in class-II CAP-dependent transcription activation
Resolution4.29 Å
Binding residue
(original residue number in PDB)		M102 R103 M105 G106 L110 N383 R385 L386 R397 F419 E420 R423 Y425 K426 S428 T429 Y430 W433 W434 Q437 H455
Binding residue
(residue number reindexed from 1)		M10 R11 M13 G14 L18 N253 R255 L256 R267 F289 E290 R293 Y295 K296 S298 T299 Y300 W303 W304 Q307 H325
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005515 protein binding
GO:0016987 sigma factor activity
Biological Process
GO:0006351 DNA-templated transcription
GO:0006352 DNA-templated transcription initiation
GO:0006355 regulation of DNA-templated transcription
GO:0009408 response to heat
GO:0010468 regulation of gene expression
GO:0045892 negative regulation of DNA-templated transcription
GO:2000142 regulation of DNA-templated transcription initiation
Cellular Component
GO:0000345 cytosolic DNA-directed RNA polymerase complex
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:1903865 sigma factor antagonist complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6pb6, PDBe:6pb6, PDBj:6pb6
PDBsum6pb6
PubMed
UniProtP00579|RPOD_ECOLI RNA polymerase sigma factor RpoD (Gene Name=rpoD)

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