Structure of PDB 6om1 Chain F Binding Site BS01

Receptor Information

>6om1 Chain F (length=332) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

NTQVTPGEVSIQLRPGAEANFMLKVHPLKKYPVDLYYLVDVSASMHNNIE
KLNSVGNDLSRKMAFFSRDFRLGFGSYVDKTVSPYISIHPECNLDCMPPH
GYIHVLSLTENITEFEKAVHRQKISGNIDTPEGGFDAMLQAAVCESHIGW
RKEAKRLLLVMTDQTSHLALDSKLAGIVCPNDGNCHLKNNVYVKSTTMEH
PSLGQLSEKLIDNNINVIFAVQGKQFHWYKDLLPLLPGTIAGEIESKAAN
LNNLVVEAYQKLISEVKVQVENQVQYFNITAICPDGSRKPGMEGCRNVTS
NDEVLFNVTVTGKNYAIIKPIGFNETAKIHIH

Ligand information

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

6om1 Chain F Residue 505 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	6om1 General structural features that regulate integrin affinity revealed by atypical alpha V beta 8.
Resolution	2.66 Å
Binding residue (original residue number in PDB)	S114 E212
Binding residue (residue number reindexed from 1)	S42 E132
Annotation score	4

Enzymatic activity

Enzyme Commision number

External links

PDB	RCSB:6om1, PDBe:6om1, PDBj:6om1
PDBsum	6om1
PubMed	31792290
UniProt	P26012\|ITB8_HUMAN Integrin beta-8 (Gene Name=ITGB8)

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