Structure of PDB 6o7i Chain F Binding Site BS01

Receptor Information

>6o7i Chain F (length=361) Species: 523850 (Thermococcus onnurineus NA1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MTERTLKVLSPLHIGTGNELTPVDIYPRENIIHVLDTERAAAAAAAAGAA
AAAAAAGAAAAAAGAAAAAAAAAAAAAAAAAAAAGAAGRKSMQIKEFIKL
NGRPYIPGSSLKGAIRTAVLYKALKECGAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAGAAAAAAAAIRYEPKRDPMKALIVRDSKPVGRKHLAVY
HVEVIGNPQPIPIWVEAIEPGAATDVEIHVDTEALRLNADYFNGLLWECL
KERGEPGEVFEDFLWEAVDEFYTAVMKYETIEVQKFSQVRSFYASLEDHS
GHVLRLGWGSGWLAMTIGLLLVEKGYKWENVRKKLGLGKKREFPKTRRLA
DGMPMGWVVLE

Ligand information

>6o7i Chain G (length=26) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

guggaaaggcgggcagaggcgguuug

..........................

Receptor-Ligand Complex Structure

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Structure summary

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PDB	6o7i Second Messenger cA4Formation within the Composite Csm1 Palm Pocket of Type III-A CRISPR-Cas Csm Complex and Its Release Path.
Resolution	3.2 Å
Binding residue (original residue number in PDB)	I14 S115 S116 K118 G119 R122 Y199 P201 K202 D204 K207 M344
Binding residue (residue number reindexed from 1)	I14 S109 S110 K112 G113 R116 Y174 P176 K177 D179 K182 M315

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003723	RNA binding

	Biological Process
GO:0051607	defense response to virus

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Molecular Function

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Biological Process

External links

PDB	RCSB:6o7i, PDBe:6o7i, PDBj:6o7i
PDBsum	6o7i
PubMed	31326272
UniProt	B6YWC2

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