Structure of PDB 6mus Chain F Binding Site BS01

Receptor Information
>6mus Chain F (length=377) Species: 342948 (Thermococcus onnurineus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MTERTLKVLSPLHIGTGNELTPVDIYPRENIIHVLDTERLVNDLMNLGEL
NEILALLKNPPAYIWKGYIEEFHLDPSDYSIYTLKIHGRKSMQIKEFIKL
NGRPYIPGSSLKGAIRTAVLYKALKECDARAVMRVVSKVNGDVARDIGRD
VLDYYMSFLSRKRADDLLEAIVFGMEPDRRSKIRYEPKRDPMKALIVRDS
KPVGRKHLAVYHVEVIGNPQPIPIWVEAIEPGAATDVEIHVDTEALRLNA
DYFNGLLWECLKERGEPGEVFEDFLWEAVDEFYTAVMKYETIEVQKFSQV
RSFYASLEDHSGHVLRLGWGSGWLAMTIGLLLVEKGYKWENVRKKLGLGK
KGSGFSREFPKTRRLADGMPMGWVVLE
Ligand information
>6mus Chain G (length=33) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guggaaaggcgggcagaggcgguuugcguauug
.................................
Receptor-Ligand Complex Structure
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PDB6mus Type III-A CRISPR-Cas Csm Complexes: Assembly, Periodic RNA Cleavage, DNase Activity Regulation, and Autoimmunity.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		G15 T16 G17 S115 S116 K118 G119 A120 R122 Y199 P201 Q234 R334 L335 G336 W337 S339 W341 M344 L366 K368 K369 K381 T382 R384
Binding residue
(residue number reindexed from 1)		G15 T16 G17 S109 S110 K112 G113 A114 R116 Y185 P187 Q220 R316 L317 G318 W319 S321 W323 M326 L348 K350 K351 K361 T362 R364
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:6mus, PDBe:6mus, PDBj:6mus
PDBsum6mus
PubMed30503773
UniProtB6YWC2

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