Structure of PDB 6m8r Chain F Binding Site BS01

Receptor Information
>6m8r Chain F (length=96) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKDLAKDSKGRFFIDR
DGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVKLLT
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain6m8r Chain F Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6m8r Structural basis for KCTD-mediated rapid desensitization of GABABsignalling.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		D87 D91 Q93
Binding residue
(residue number reindexed from 1)		D60 D64 Q66
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0051260 protein homooligomerization

View graph for
Biological Process
External links
PDB RCSB:6m8r, PDBe:6m8r, PDBj:6m8r
PDBsum6m8r
PubMed30814734
UniProtQ68DU8|KCD16_HUMAN BTB/POZ domain-containing protein KCTD16 (Gene Name=KCTD16)

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