Structure of PDB 6jp5 Chain F Binding Site BS01

Receptor Information
>6jp5 Chain F (length=973) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FPSAVTIKSWVDKMQEDLVTLAKTASGVHQLVDIYEKYQDLYTVEPNNAR
QLVEIAARDIEKLLSNRSKALVRLALEAEKVQAAHQWREDFASNEVVYYN
AKDDLDPEKNDSEPGSQRIKPVFIDDANFRRQVSYQHAAVHIPTDIYEGS
TIVLNELNWTSALDDVFKKNREEDPSLLWQVFGSATGLARYYPASPWVDN
SRTPNKIDLYDVRRRPWYIQGAASPKDMLILVDVSGSVSGLTLKLIRTSV
SEMLETLSDDDFVNVASFNSNAQDVSCFQHLVQANVRNKKVLKDAVNNIT
AKGITDYKKGFSFAFEQLLNYNVSRANCNKIIMLFTDGGEERAQEIFAKY
NKDKKVRVFTFSVGQHNYDRGPIQWMACENKGYYYEIPSIGAIRINTQEY
LDVLGRPMVLAGDKAKQVQWTNVYLDALELGLVITGTLPVFNITGQFENK
TNLKNQLILGVMGVDVSLEDIKRLTPRFTLCPNGYYFAIDPNGYVLLHPN
LQPKPIGVGIPTINLRKRRPNVQNPKSQEPVTLDFLDAELENDIKVEIRN
KMIDGESGEKTFRTLVKSQDERYIDKGNRTYTWTPVNGTDYSLALVLPTY
SFYYIKAKIEETITQARYSETLKPDNFEESGYTFLAPRDYCSDLKPSDNN
TEFLLNFNEFIDRKTPNNPSCNTDLINRVLLDAGFTNELVQNYWSKQKNI
KGVKARFVVTDGGITRVYPKEAGENWQENPETYEDSFYKRSLDNDNYVFT
APYFNKSGPGAYESGIMVSKAVEIYIQGKLLKPAVVGIKIDVNSWIENFT
KDCKRNSDVMDCVILDDGGFLLMANHDDYTNQIGRFFGEIDPSLMRHLVN
ISVYAFNKSYDYQSVCEPGAASKQSCITEQTQYFFDNDSKSFSGVLDCGN
CSRIFHVEKLMNTNLIFIMVESKGTCPCDTRLLIQAEQTSDGPDPCDMVK
QPRYRKGPDVCFDNNVLEDYTDC
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain6jp5 Chain A Residue 1914 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6jp5 Molecular Basis for Ligand Modulation of a Mammalian Voltage-Gated Ca2+Channel.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		S263 S265 T333
Binding residue
(residue number reindexed from 1)		S235 S237 T305
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:6jp5, PDBe:6jp5, PDBj:6jp5
PDBsum6jp5
PubMed31150622
UniProtP13806|CA2D1_RABIT Voltage-dependent calcium channel subunit alpha-2/delta-1 (Gene Name=CACNA2D1)

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