Structure of PDB 6jmt Chain F Binding Site BS01

Receptor Information
>6jmt Chain F (length=346) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LRSSDVCADCNGPDPSWASVNRGTFICDECCSVHRSLGRHISQVRHLKHT
AWPPTLLQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKA
EFIRAKYQMLAFVHRLPCREDDSVTAKDLSKQLHSSVRTGNLETCLRLLS
LGAQANFFHPEKGSTPLHVASKAGQILQAELLAVYGADPGTQDSSGKTPV
DYARQGGHHELAERLIEIQYELTDRLAFYLCGRKPDHKSGQHFLIPQRAD
AALDLSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVWLATQNH
SVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQ
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6jmt GIT/PIX Condensates Are Modular and Ideal for Distinct Compartmentalized Cell Signaling.
Resolution2.8 Å
Binding residue
(original residue number in PDB)
A266 K267 K269 L270 L277 L281 S324 T326 R327 G330 F337 D348
Binding residue
(residue number reindexed from 1)
A262 K263 K265 L266 L273 L277 S312 T314 R315 G318 F325 D336
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005096 GTPase activator activity
Biological Process
GO:0007420 brain development
GO:0032012 regulation of ARF protein signal transduction

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Molecular Function

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Biological Process
External links
PDB RCSB:6jmt, PDBe:6jmt, PDBj:6jmt
PDBsum6jmt
PubMed32780989
UniProtQ9JLQ2|GIT2_MOUSE ARF GTPase-activating protein GIT2 (Gene Name=Git2)

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