Structure of PDB 6e0p Chain F Binding Site BS01
Receptor Information
>6e0p Chain F (length=80) Species:
9606
(Homo sapiens) [
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RDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTY
TEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Ligand information
>6e0p Chain I (length=145) [
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atcaatatccacctgcagattctaccaaaagtgtatttggaaactgctcc
atcaaaaggcatgttcagctctgtgagtgaaactccatcatcacaaagaa
tattctgagaatgcttccgtttgccttttatatgaacttcctgat
Receptor-Ligand Complex Structure
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PDB
6e0p
Atomic resolution cryo-EM structure of a native-like CENP-A nucleosome aided by an antibody fragment.
Resolution
2.6 Å
Binding residue
(original residue number in PDB)
P32 R36 K44 R45
Binding residue
(residue number reindexed from 1)
P10 R14 K22 R23
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003677
DNA binding
GO:0003723
RNA binding
GO:0005515
protein binding
GO:0030527
structural constituent of chromatin
GO:0046982
protein heterodimerization activity
Biological Process
GO:0006325
chromatin organization
GO:0006334
nucleosome assembly
GO:0032200
telomere organization
GO:0045653
negative regulation of megakaryocyte differentiation
GO:0061644
protein localization to CENP-A containing chromatin
Cellular Component
GO:0000781
chromosome, telomeric region
GO:0000786
nucleosome
GO:0005576
extracellular region
GO:0005634
nucleus
GO:0005654
nucleoplasm
GO:0005694
chromosome
GO:0016020
membrane
GO:0032991
protein-containing complex
GO:0043505
CENP-A containing nucleosome
GO:0070062
extracellular exosome
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:6e0p
,
PDBe:6e0p
,
PDBj:6e0p
PDBsum
6e0p
PubMed
31127102
UniProt
P62805
|H4_HUMAN Histone H4 (Gene Name=H4C1)
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