Structure of PDB 6d9k Chain F Binding Site BS01

Receptor Information
>6d9k Chain F (length=755) Species: 349102 (Cereibacter sphaeroides ATCC 17025) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RQLVSNGFEVNLPDQVEVIVRDLPDPSKVKEERTRLMGYWFVHWFDGKLF
HLRIKAGGPNVDGEHRAIRTAEHPWLLRARLDDALEEALPKYAAVKKRPF
TFLAQKDELIDAAATAAGLSHRLLNSFKVIPRFALSPKIYEPVDGTTRVG
VFVTIGMRYDIEASLRDLLEAGIDLRGMYVVRRKRQRGLLGRVRAISDDM
VQLFEETDLASVNVNDAKLEGSKENFTRCLSALLGHNYKKLLNALDDQEA
GYRTGPRFDDAVRRMGEFLAKKPIRLADNINAQVGDRIVFSNEGQARNVR
LAPKVEYVFDRTGAKSAEYAWRGLSQFGPFDRPSFANRSPRILVVYPSST
QGKVENFLSAFRDGMGSNYSGFSKGFVDLMGLTKVEFVMCPVEVSSADRN
GAHTKYNSAIEDKLAGAGEVHAGIVVLFEDHARLPDDRNPYIHTKSLLLT
LGVPTQQVRMPTVLLEPKSLQYTLQNFSIATYAKLNGTPWTVNHDKAIND
ELVVGMGLAELSGSRTEKRQRFVGITTVFAGDGSYLLGNVSKECEYEGYS
DAIRESMTGILRELKKRNNWRPGDTVRVVFHAHRPLKRVDVASIVFECTR
EIGSDQNIQMAFVTVSHDHPFVLIDRSERGLEAYKGSTARKGVFAPPRGA
ISRVGRLTRLLAVNSPQLIKRANTPLPTPLLVSLHPDSTFKDVDYLAEQA
LKFTSLSWRSTLPAATPVTIFYSERIAELLGRLKSIPNWSSANLNIKLKW
SRWFL
Ligand information
Receptor-Ligand Complex Structure
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PDB6d9k Accommodation of Helical Imperfections in Rhodobacter sphaeroides Argonaute Ternary Complexes with Guide RNA and Target DNA.
Resolution2.0 Å
Binding residue
(original residue number in PDB)
P43 P45 W63 R151 G175 M176 Y178 L211 E242 G243 S244 R275 A454 Y463 K467 Q478 Q479 R481 T484 T495 N498 F499 K506 R537 R543 R606 K609 R610 K692 R731 S732 P735 A737 F743 R754 L777
Binding residue
(residue number reindexed from 1)
P24 P26 W44 R132 G156 M157 Y159 L189 E220 G221 S222 R253 A432 Y441 K445 Q456 Q457 R459 T462 T473 N476 F477 K484 R515 R521 R584 K587 R588 K670 R709 S710 P713 A715 F721 R732 L755
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0004520 DNA endonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0044355 clearance of foreign intracellular DNA

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Molecular Function

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Biological Process
External links
PDB RCSB:6d9k, PDBe:6d9k, PDBj:6d9k
PDBsum6d9k
PubMed29996105
UniProtA4WYU7|AGO_CERS5 Protein argonaute (Gene Name=ago)

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