Structure of PDB 6cnl Chain F Binding Site BS01

Receptor Information
>6cnl Chain F (length=187) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DHYKAKATRHIFLIRASQYHTLTPLGREQAELTGLRLASLGLKFNKIVHS
SMTRAIETTDIISRHLPGVCKVSTDLLREGAPIEPDPPVPEAVQYYEDGA
RIEAAFRNYIHRADARQEEDSYEIFICHANVIRYIVCRALQFPPEGWLRL
SLNNGSITHLVIRPNGRVALRTLGDTGFMPPDKITRS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6cnl Functional role of PGAM5 multimeric assemblies and their polymerization into filaments.
Resolution2.6 Å
Binding residue
(original residue number in PDB)
H213 R214 Q243 G268
Binding residue
(residue number reindexed from 1)
H111 R112 Q141 G166
Enzymatic activity
Enzyme Commision number 3.1.3.16: protein-serine/threonine phosphatase.
External links
PDB RCSB:6cnl, PDBe:6cnl, PDBj:6cnl
PDBsum6cnl
PubMed30705304
UniProtQ96HS1|PGAM5_HUMAN Serine/threonine-protein phosphatase PGAM5, mitochondrial (Gene Name=PGAM5)

[Back to BioLiP]