Structure of PDB 6c4u Chain F Binding Site BS01
Receptor Information
>6c4u Chain F (length=126) Species:
4932
(Saccharomyces cerevisiae) [
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NIVFRVISTTGQIPIRDFSADISQVLKEKRSIKKVWTFGRNPACDYHLGN
ILPVSNKHFQILLGEDGNLLLNDISTNGTWLNGQKVEKNSYQLLSQGDEI
TVRTDPTGTILSLVIFINDKFKQSLE
Ligand information
>6c4u Chain L (length=6) Species:
9606
(Homo sapiens) [
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LPTPPL
Receptor-Ligand Complex Structure
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PDB
6c4u
Generating a recombinant phosphothreonine-binding domain for a phosphopeptide of the human transcription factor, c-Myc.
Resolution
2.6 Å
Binding residue
(original residue number in PDB)
R70 S85 N86 T106 N107
Binding residue
(residue number reindexed from 1)
R40 S55 N56 T76 N77
Enzymatic activity
Enzyme Commision number
2.7.12.1
: dual-specificity kinase.
External links
PDB
RCSB:6c4u
,
PDBe:6c4u
,
PDBj:6c4u
PDBsum
6c4u
PubMed
29763736
UniProt
P22216
|RAD53_YEAST Serine/threonine-protein kinase RAD53 (Gene Name=RAD53)
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