Structure of PDB 6c1a Chain F Binding Site BS01

Receptor Information
>6c1a Chain F (length=68) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYL
GNTVDLSSFDFRTGKMMP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6c1a Structural basis for the ability of MBD domains to bind methyl-CG and TG sites in DNA.
Resolution2.05 Å
Binding residue
(original residue number in PDB)		R166 S168 G169 L170 S171
Binding residue
(residue number reindexed from 1)		R19 S21 G22 L23 S24
Binding affinityPDBbind-CN: Kd=7.2uM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:6c1a, PDBe:6c1a, PDBj:6c1a
PDBsum6c1a
PubMed29567833
UniProtQ9UBB5|MBD2_HUMAN Methyl-CpG-binding domain protein 2 (Gene Name=MBD2)

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