Structure of PDB 6avg Chain F Binding Site BS01

Receptor Information
>6avg Chain F (length=275) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAASPREEPRAP
WIEQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMYG
CDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAA
REAEQRRAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6avg Divergent T-cell receptor recognition modes of a HLA-I restricted extended tumour-associated peptide.
Resolution2.6 Å
Binding residue
(original residue number in PDB)
Y7 R62 I66 Y67 T73 S77 N80 L81 Y84 Y99 T143 K146 W147 E152 Q155 R156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 R62 I66 Y67 T73 S77 N80 L81 Y84 Y99 T143 K146 W147 E152 Q155 R156 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation

View graph for
Biological Process
External links
PDB RCSB:6avg, PDBe:6avg, PDBj:6avg
PDBsum6avg
PubMed29531227
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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