Structure of PDB 5wkh Chain F Binding Site BS01

Receptor Information
>5wkh Chain F (length=274) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFYTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEDGSHTIQIMYG
CDVGPDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAA
HAAEQQRAYLEGRCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRW
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5wkh Germline bias dictates cross-serotype reactivity in a common dengue-virus-specific CD8(+) T cell response.
Resolution3.2 Å
Binding residue
(original residue number in PDB)
Y7 Y9 E63 N66 T73 V76 D77 Y84 I95 I97 Y99 D116 T143 K146 W147 A152 Q155 Q156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 Y9 E63 N66 T73 V76 D77 Y84 I95 I97 Y99 D116 T143 K146 W147 A152 Q155 Q156 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5wkh, PDBe:5wkh, PDBj:5wkh
PDBsum5wkh
PubMed28945243
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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