Structure of PDB 5vzw Chain F Binding Site BS01

Receptor Information
>5vzw Chain F (length=77) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VLECGVCEDVFSLQGDKVPRLLLCGHTVCHDCLTRLPLHGRAIRCPFDRQ
VTDLGDSGVWGLKKNFALLELLERLQN
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5vzw Chain F Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5vzw Structure and catalytic activation of the TRIM23 RING E3 ubiquitin ligase.
Resolution2.278 Å
Binding residue
(original residue number in PDB)		C51 H53 C72 D75
Binding residue
(residue number reindexed from 1)		C24 H26 C45 D48
Annotation score4
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
External links
PDB RCSB:5vzw, PDBe:5vzw, PDBj:5vzw
PDBsum5vzw
PubMed28681414
UniProtP36406|TRI23_HUMAN E3 ubiquitin-protein ligase TRIM23 (Gene Name=TRIM23)

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