Structure of PDB 5oql Chain F Binding Site BS01

Receptor Information
>5oql Chain F (length=429) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KAELDRIRRYKQAQKKYGRGPRVDIKKLRRTLTNLENKYKTAALKAKEAE
ILLENQTGFLEPEGELERTYKVRQDEIVKEVAVEVAQKKFELKLTELGPY
TCEYSRNGRDLILAGRKGHVATMDWREGKLGCELQLGETVRDARFLHNNQ
FFAVAQKKYVYIYDHNGVEIHCLRKHVEVSHMEFLPYHFLLATLSISGQL
KYQDTSTGQIVAEIATKHGTPVSLTQNPYNAILHIGQQNGTVTLWSPNST
DPLVKLLAHRGPVRSLAVDREGRYMVSTGQDNKMCIWDIRNFKEAVNSYF
TRAPATSVAISDTGLTAVGWGTHTTIWKGLFNKERPVQVKVDSPYMTWGG
QGQVVERVRWCPFEDILGIGHNEGFSSIIVPGAGEANYDALEVNPFETKK
QRQEGEVKALLNKLQPEMIALDPNFIGNL
Ligand information
>5oql Chain 1 (length=1350) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggggggauguccgggucgcccugggcaccucuccgcggcagcgcaagccg
uuucauacgucgccgcaaucgcgaggggcuccaagcggucgccggcgagc
accaccccagccccgcgccgcccccagcgcaccgcgcgcaggggggccgg
cgcggcaucugggaagacuccuaaggcgcaagggaauaccccgugcgccg
gggguugggcucugugggugcuuggccgcuggccagaccuacuucaaagc
caccggggguaccuaccgguugucucggucgggccuccucuuggggcgcc
uaggcggugucuucgggucgcgugcagccucccguccucgccugccgaca
gcgcucuggggaauucaggaggggaaagcagaugugccccgcggcgagac
uggcgccggacgagcugcuggggcacgcggguacgcuagccgcacgauag
uuaccugguugauucuuagucauaugcuugucucaaagccaugcgucuaa
guauaagcaauuacagcgaaacugcgaauggcucauuaaaucaguuaucg
uuuauuugauaguauggauaaccgugguaauucuagagcuaauacaugcg
uauuuauuagggugauucauaauaacuucucgaaucgcacggccuugcgc
cggcgaugguucauucaaauuucugcccuaucaacuuucgacggcugggu
auuggccagccguggugacaacggguaagagaggagccugagaaacggcu
acuacauccaaggaagggcaggcgccaaauuacccaaucccgacacgggg
agguagugacaauaaauacugauacagggcuccgggucuuguaauuggaa
ugaguacaauuuaaaucccuuaacgaggaacaauuggagggcaagucugg
ugccagcagccgcgguaauucccuccaauagcguauauugcucguaguug
aaccugauuaauagggacagucgggggcgucaguauucaauugucagagg
ugaaauucuuggauuuauugaagacuaacaacugcgaaagcauucgccaa
ggauguuuucauuaaucaggaacgauuagggaucggacggcguuuauuuu
ugacccguucggcaccuuacgauaaaucaaaauguuugggaguauggucg
caugacggaagggcaccaccagggguggagccugcgcgcgcgcuacacug
acagagccagcgaguacucccuuggccgagaggcccggguaaacucuguc
gugcugaggaaucccuaguaagcgcaagucaucagcuugcguugauuacg
ucccugcccuuuguacacaccgcccgucgcuacuaccgauagaggaagua
<<.<<<.<<<<<<<<....>>>>>>>>>>>.>.>.<<<<.<..>..>>>>
.........<<<<<<<.<<<<<..<<<<>>>>..>>>>>.>>.>>>>>..
..<..<<<<<..<<<<<<<<<<<<<.<<<<.....>>>>..>>>>>.>>>
>>>>>...>>>>>..>........<<<<<<.<<<.....>>>.>>>>>>.
........................<<<...>>>.................
....<<<<<..<<<<<<<<.....>>>>>.>>>>>>>>.....<<<<<<.
..<<<<<<<....<<<<..<<.....>>..>>>>....>>>>.>>>....
>>>>>>...........................<<<<.<<<<<<<..<.<
<<<..>>>>.>..>>>>>.>>.>>>><<<<.<.....>.>>>>.......
..................<..<<<<<<...<.<<..<<<<.<<<<<....
<<....<<.......>>...>>.>>......<<<.......<<<..<<..
<<....<<<.......<.<..<..<<<.....>>>..>.....>>....<
...<<<<<<.<......>.>>>>>>.....>...<<<<.<<<<.....>>
>>>>>>....>>>...>>>>..>>>.<<<....<<<....<<<<<<<<..
.....>>>>>>>>>>>......>>>...>>><<.<<<..........>>>
.>>.<.<<<..>>>.>.>>>>>>........<<<...<<<<<...>>>>.
>>>>..>>...>.>....<<<<<<<<<<<<<...>>>>>>>>.>>>>>..
...<<..<...........>..>>.........<<<<<<.......<<<.
...>>>................>>>>>>..>>>>>>.>.<.<<...<<<.
<<.....>>.....<<<<<.<<...<<<<..<<<.<<<<<<.....<<<.
.....>>>........>>>>>>.>>>.......<<....>>...>>>>..
>>.>>>.>>....>>>...>>.>..<..<<..<<<<<<<<.<<<......
.>>>>>>>>>>>..>>.....<....>....>..................
..<<<<<<<<<<<<<..<<.<<<<<<..<<<.<<<..>>>.>>>.....<
<<<<<<..............<<.<<<<....>>>>.>>.....>>>>>>>
..........>>>>>>....<<<<<<<<.......>>>>>>>>......>
>...>>>>>>>............>>>>>>.<<<<.<<......>>.>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5oql 3.2- angstrom -resolution structure of the 90S preribosome before A1 pre-rRNA cleavage.
Resolution3.2 Å
Binding residue
(original residue number in PDB)
K66 R70 Y110 K111 R113 Q190 K198 H205 R214 K215 E218 S237 Q249 I250 E253 T290 L297 R300 K323 N337 S338 Y339 F340 R342 T362 W367 K380 V381 D382 P384 G392 K439 R442 Q443
Binding residue
(residue number reindexed from 1)
K26 R30 Y70 K71 R73 Q150 K158 H165 R174 K175 E178 S197 Q209 I210 E213 T250 L257 R260 K283 N297 S298 Y299 F300 R302 T322 W327 K340 V341 D342 P344 G352 K399 R402 Q403
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Cellular Component
GO:0005730 nucleolus
GO:0030686 90S preribosome
GO:0032040 small-subunit processome

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:5oql, PDBe:5oql, PDBj:5oql
PDBsum5oql
PubMed28967883
UniProtG0RZ99

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