Structure of PDB 5njk Chain F Binding Site BS01
Receptor Information
>5njk Chain F (length=142) Species:
9606
(Homo sapiens) [
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HQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKAERKFF
KGFKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAF
SYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERK
Ligand information
>5njk Chain M (length=7) Species:
9606
(Homo sapiens) [
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AYIGPYL
Receptor-Ligand Complex Structure
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PDB
5njk
A Numb-Mdm2 fuzzy complex reveals an isoform-specific involvement of Numb in breast cancer.
Resolution
3.13 Å
Binding residue
(original residue number in PDB)
R53 I111 E112 V114 S115 F116 C117 R132 W139 S155 H156 G159 F162
Binding residue
(residue number reindexed from 1)
R31 I84 E85 V87 S88 F89 C90 R105 W112 S128 H129 G132 F135
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5njk
,
PDBe:5njk
,
PDBj:5njk
PDBsum
5njk
PubMed
29269425
UniProt
P49757
|NUMB_HUMAN Protein numb homolog (Gene Name=NUMB)
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