Structure of PDB 5kn5 Chain F Binding Site BS01

Receptor Information
>5kn5 Chain F (length=39) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SHTQFCFHGTCRFLVQEDKPACVCHSGYVGARCEHADLL
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5kn5 Chain C Residue 101 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5kn5 Structural basis of selectivity and neutralizing activity of a TGF alpha /epiregulin specific antibody.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		H18 H35
Binding residue
(residue number reindexed from 1)		H8 H25
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5kn5, PDBe:5kn5, PDBj:5kn5
PDBsum5kn5
PubMed27543934
UniProtP01135|TGFA_HUMAN Protransforming growth factor alpha (Gene Name=TGFA)

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