Structure of PDB 5jqi Chain F Binding Site BS01

Receptor Information
>5jqi Chain F (length=276) Species: 364106 (Escherichia coli UTI89) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FACKTANGTAIPGSANVYVNLAPAVNVGQNLVVDLSTQIFCHNDYPETIT
DYVTLQRGSAYGGVLSSFSGTVKYNGSSYPFPTTSETPRVVYNSRTDKPW
PVALYLTPVSSAGGVAIKAGSLIAVLILRQTNNYNSDDFQFVWNIYANND
VVVPTGGCDVSARDVTVTLPDYPGSVPIPLTVYCAKSQNLGYYLSGTTAD
AGNSIFTNTASFSPAQGVGVQLTRNGTIIPANNTVSLGAVGTSAVSLGLT
ANYARTGGQVTAGNVQSIIGVTFVYQ
Ligand information
>5jqi Chain E (length=12) Species: 364106 (Escherichia coli UTI89) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ADVTITVNGKVV
Receptor-Ligand Complex Structure
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PDB5jqi Evolutionary fine-tuning of conformational ensembles in FimH during host-pathogen interactions.
Resolution1.962 Å
Binding residue
(original residue number in PDB)		A165 R166 D167 V168 T169 V170 T171 L172 Y175 Y256 T264 A265 G266 V268 Q269 S270 I271 I272 G273 V274 T275 F276
Binding residue
(residue number reindexed from 1)		A162 R163 D164 V165 T166 V167 T168 L169 Y172 Y253 T261 A262 G263 V265 Q266 S267 I268 I269 G270 V271 T272 F273
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0007155 cell adhesion
GO:0043709 cell adhesion involved in single-species biofilm formation
Cellular Component
GO:0009289 pilus

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Biological Process
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Cellular Component
External links
PDB RCSB:5jqi, PDBe:5jqi, PDBj:5jqi
PDBsum5jqi
PubMed28246638
UniProtQ1R2J4

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