Structure of PDB 5ffo Chain F Binding Site BS01

Receptor Information
>5ffo Chain F (length=242) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DYPVDLYYLMDLSASMDDDLNTIKELGSRLSKEMSKLTSNFRLGFGSFVE
KPVSPFVKTTPEEIANPCSSIPYFCLPTFGFKHILPLTNDAERFNEIVKN
QKISANIDTPEGGFDAIMQAAVCKEKIGWRNDSLHLLVFVSDADSHFGMD
SKLAGIVCPNDGLCHLDSKNEYSMSTVLEYPTIGQLIDKLVQNNVLLIFA
VTQEQVHLYENYAKLIPGATVGLLQKDSGNILQLIISAYEEL
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain5ffo Chain F Residue 2001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5ffo Force interacts with macromolecular structure in activation of TGF-beta.
Resolution3.49 Å
Binding residue
(original residue number in PDB)		S127 D130 D131 D254
Binding residue
(residue number reindexed from 1)		S15 D18 D19 D142
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5ffo, PDBe:5ffo, PDBj:5ffo
PDBsum5ffo
PubMed28117447
UniProtP18564|ITB6_HUMAN Integrin beta-6 (Gene Name=ITGB6)

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