Structure of PDB 5eom Chain F Binding Site BS01

Receptor Information
>5eom Chain F (length=339) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GAMDIAAQAKLVYHLNKYYNEKCQARKAAIAKTIREVCKVVSDVLKEVEV
QEPRFISSLNEMDNRYEGLEVISPTEFEVVLYLNQVFNFVDGSLPGCAVL
KLSSLWVEFITASGYLSARKIRSRFQTLVAQAVDKCSYRDVVKMVADTSE
VKLRIRDRYVVQITPAFKCTGIWPRSAAHWPLPIPWPGPNRVAEVKAEGF
NLLSKESDAWVLQFAEAENRLQMGGCRKKCLSILKTLRDRHLELPGQPLN
NYHMKTLVSYECEKHPRESDWDESCLGDRLNGILLQLISCLQCRRCPHYF
LPNLDLFQGKPHSALENAAKQTWRLAREILTNPKSLEKL
Ligand information
Ligand IDTMO
InChIInChI=1S/C3H9NO/c1-4(2,3)5/h1-3H3
InChIKeyUYPYRKYUKCHHIB-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.370
OpenEye OEToolkits 1.7.0		C[N+](C)(C)[O-]
ACDLabs 12.01[O-][N+](C)(C)C
FormulaC3 H9 N O
Nametrimethylamine oxide
ChEMBL
DrugBank
ZINCZINC000000895494
PDB chain5eom Chain F Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5eom Structural and biochemical characterization of the cell fate determining nucleotidyltransferase fold protein MAB21L1.
Resolution2.55 Å
Binding residue
(original residue number in PDB)		S144 Y145
Binding residue
(residue number reindexed from 1)		S137 Y138
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.7.-
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0005525 GTP binding
GO:0016779 nucleotidyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0001654 eye development
GO:0008283 cell population proliferation
GO:0008284 positive regulation of cell population proliferation
GO:0009653 anatomical structure morphogenesis
GO:0043010 camera-type eye development
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5eom, PDBe:5eom, PDBj:5eom
PDBsum5eom
PubMed27271801
UniProtQ13394|MB211_HUMAN Putative nucleotidyltransferase MAB21L1 (Gene Name=MAB21L1)

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