Structure of PDB 5e18 Chain F Binding Site BS01

Receptor Information
>5e18 Chain F (length=335) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SDPVRQYLHEIGQVPLLTLEEEVELARKVEEGMEAIKKLSEITGLDPDLI
REVVRAKILGSARVRHIPGLKETLDPKTVEEIDQKLKSLPKEHKRYLHIA
REGEAARQHLIEANLRLVVSIAKKYTGRGLSFLDLIQEGNQGLIRAVEKF
EYKRRFKFSTYATWWIRQAINRAIADQARTIRIPVHMVETINKLSRTARQ
LQQELGREPTYEEIAEAMGPGWDAKRVEETLKIAQEPVSLEGDFIPDEHL
PSPVDAATQSLLSEELEKALSKLSEREAMVLKLRKGLIDGREHTLEEVGA
FFGVTRERIRQIENKALRKLKYHESRTRKLRDFLD
Ligand information
Receptor-Ligand Complex Structure
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PDB5e18 Multiplexed protein-DNA cross-linking: Scrunching in transcription start site selection.
Resolution3.3 Å
Binding residue
(original residue number in PDB)		V81 L85 R193 L194 T203 S208 F209 R231 F233 K234 S236 T237 Y238 T240 W241
Binding residue
(residue number reindexed from 1)		V4 L8 R116 L117 T126 S131 F132 R154 F156 K157 S159 T160 Y161 T163 W164
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0016987 sigma factor activity
GO:0046872 metal ion binding
Biological Process
GO:0006352 DNA-templated transcription initiation
GO:0006355 regulation of DNA-templated transcription
GO:0010468 regulation of gene expression
GO:2000142 regulation of DNA-templated transcription initiation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5e18, PDBe:5e18, PDBj:5e18
PDBsum5e18
PubMed26941320
UniProtQ5SKW1

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