Structure of PDB 5cch Chain F Binding Site BS01

Receptor Information
>5cch Chain F (length=266) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKK
KKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDII
GEFKVPMNTVDFGHVTEEWRDLQSAEKEKLGDICFSLRYVPTAGKLTVVI
LEAKNLKKSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPF
EQIQKVQVVVTVLDYDNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQ
WHTLQVEEEVDAMLAV
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5cch Chain F Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5cch Architecture of the synaptotagmin-SNARE machinery for neuronal exocytosis.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		D172 D230 F231 D232
Binding residue
(residue number reindexed from 1)		D32 D90 F91 D92
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:5cch, PDBe:5cch, PDBj:5cch
PDBsum5cch
PubMed26280336
UniProtP21707|SYT1_RAT Synaptotagmin-1 (Gene Name=Syt1)

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