Structure of PDB 5c0b Chain F Binding Site BS01
Receptor Information
>5c0b Chain F (length=275) Species:
9606
(Homo sapiens) [
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GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWE
Ligand information
>5c0b Chain H (length=10) Species:
9606
(Homo sapiens) [
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RQFGPDFPTI
Receptor-Ligand Complex Structure
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PDB
5c0b
Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
Resolution
2.03 Å
Binding residue
(original residue number in PDB)
Y7 M45 E63 K66 V67 H70 D77 T80 L81 R97 Y99 T143 K146 W147 Q155 L156 Y159 T163 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 M45 E63 K66 V67 H70 D77 T80 L81 R97 Y99 T143 K146 W147 Q155 L156 Y159 T163 W167 Y171
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5c0b
,
PDBe:5c0b
,
PDBj:5c0b
PDBsum
5c0b
PubMed
27183389
UniProt
P04439
|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)
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