Structure of PDB 5c0a Chain F Binding Site BS01
Receptor Information
>5c0a Chain F (length=276) Species:
9606
(Homo sapiens) [
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GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWEP
Ligand information
>5c0a Chain H (length=10) Species:
9606
(Homo sapiens) [
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MVWGPDPLYV
Receptor-Ligand Complex Structure
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PDB
5c0a
Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
Resolution
2.46 Å
Binding residue
(original residue number in PDB)
Y7 E63 K66 A69 H70 T73 V76 D77 Y99 Y116 T143 K146 W147 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 E63 K66 A69 H70 T73 V76 D77 Y99 Y116 T143 K146 W147 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5c0a
,
PDBe:5c0a
,
PDBj:5c0a
PDBsum
5c0a
PubMed
27183389
UniProt
P04439
|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)
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