Structure of PDB 5brm Chain F Binding Site BS01
Receptor Information
>5brm Chain F (length=160) Species:
9606
(Homo sapiens) [
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DLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGT
NIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTI
LKRLFRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRREL
APLQELIEKL
Ligand information
>5brm Chain L (length=12) Species:
9606
(Homo sapiens) [
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TMKRNPSFMDYF
Receptor-Ligand Complex Structure
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PDB
5brm
Structural basis for Mob1-dependent activation of the core Mst-Lats kinase cascade in Hippo signaling.
Resolution
2.651 Å
Binding residue
(original residue number in PDB)
R92 Y93 Y95 K153 R154 R157 Y163 F167 E200 E206 L207
Binding residue
(residue number reindexed from 1)
R41 Y42 Y44 K102 R103 R106 Y112 F116 E149 E155 L156
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5brm
,
PDBe:5brm
,
PDBj:5brm
PDBsum
5brm
PubMed
26108669
UniProt
Q9H8S9
|MOB1A_HUMAN MOB kinase activator 1A (Gene Name=MOB1A)
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