Structure of PDB 5akm Chain F Binding Site BS01

Receptor Information
>5akm Chain F (length=174) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NVSGISAYLLGLIISDGGLYKLKYKGNRSEYRVVITQKSENLIKQHIAPL
MQFLIDELNVKSKIQIVKGDTRYELRVSSKKLYYYFANMLERIRLFNMRE
QIAFIKGLYVAEGDKTLKRLRIWNKNKALLEIVSRWLNNLGVRNTIHLDD
HRHGVYVLNISLRDRIKFVHTILS
Ligand information
Receptor-Ligand Complex Structure
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PDB5akm Engineering a Nickase on the Homing Endonuclease I-Dmoi Scaffold.
Resolution2.4 Å
Binding residue
(original residue number in PDB)
D21 T41 Q42 K43 T76 R77 R124 T150 H152 D154 H156 R157 N164 S166 L167
Binding residue
(residue number reindexed from 1)
D16 T36 Q37 K38 T71 R72 R119 T145 H147 D149 H151 R152 N159 S161 L162
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
Biological Process
GO:0006314 intron homing
GO:0016539 intein-mediated protein splicing

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Molecular Function

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Biological Process
External links
PDB RCSB:5akm, PDBe:5akm, PDBj:5akm
PDBsum5akm
PubMed26045557
UniProtP21505|DMO1_DESMO Homing endonuclease I-DmoI

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