Structure of PDB 4u0d Chain F Binding Site BS01

Receptor Information

>4u0d Chain F (length=211) Species: 11698 (Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

PIVQNQMVHQCISPRTLNAWVKVVEEKAFSPEVIPMFSALSCGATPQDLN
TMLNTVGGHQAAMQMLKETINEEAAEWDRLHPVHPGQMREPRGSDIAGTT
STLQEQIGWMTHNPPIPVGEIYKRWIILGLNKIVRMYSPTSILDIRQGPK
EPFRDYVDRFYKTLRAEQASQEVKNAATETLLVQNANPDCKTILKALGPG
ATLEEMMTACQ

Ligand information

>4u0d Chain M (length=9) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

SPSGVFTFG

Receptor-Ligand Complex Structure

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Structure summary

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PDB	4u0d Host Cofactors and Pharmacologic Ligands Share an Essential Interface in HIV-1 Capsid That Is Lost upon Disassembly.
Resolution	3.0 Å
Binding residue (original residue number in PDB)	I37 R143 R173 Q176 A177
Binding residue (residue number reindexed from 1)	I34 R135 R165 Q168 A169

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Biological Process
GO:0016032	viral process

View graph for
Biological Process

External links

PDB	RCSB:4u0d, PDBe:4u0d, PDBj:4u0d
PDBsum	4u0d
PubMed	25356722
UniProt	P12493\|GAG_HV1N5 Gag polyprotein (Gene Name=gag)

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