Structure of PDB 4mji Chain F Binding Site BS01

Receptor Information
>4mji Chain F (length=275) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRTEPRAP
WIEQEGPEYWDRNTQIFKTNTQTYRENLRIALRYYNQSEAGSHTWQTMYG
CDVGPDGRLLRGHNQYAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAA
REAEQLRAYLEGLCVEWLRRHLENGKETLQRADPPKTHVTHHPVSDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWE
Ligand information
>4mji Chain H (length=8) Species: 11676 (Human immunodeficiency virus 1) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
TAFTIPSI
Receptor-Ligand Complex Structure
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PDB4mji Molecular basis of a dominant T cell response to an HIV reverse transcriptase 8-mer epitope presented by the protective allele HLA-B*51:01
Resolution2.99 Å
Binding residue
(original residue number in PDB)
Y7 Y9 N63 I66 F67 N70 T73 Y74 N77 I80 Y84 Y99 Y116 T143 W147 E152 L156 Y159 L163 W167
Binding residue
(residue number reindexed from 1)
Y7 Y9 N63 I66 F67 N70 T73 Y74 N77 I80 Y84 Y99 Y116 T143 W147 E152 L156 Y159 L163 W167
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:4mji, PDBe:4mji, PDBj:4mji
PDBsum4mji
PubMed24600035
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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