Structure of PDB 4laj Chain F Binding Site BS01

Receptor Information
>4laj Chain F (length=334) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VWKEATTTLFCASDAKAYDTEVHNVWATHACVPTDPNPQEVKLENVTENF
NMWKNNMVEQMHEDIISLWDQSLKPCVKLTGGSVITQACPKVSFEPIPIH
YCAPAGFAILKCNDKKFNGTGPCTNVSTVQCTHGIRPVVSTQLLLNGSLA
EEEIVIRSENFTNNAKTIIVQLNESVVINCTRPNNGDIRQAHCNLSKTQW
ENTLEQIAIKLKEQFGNNKTIIFNPSSGGDPEIVTHSFNCGGEFFYCNST
QLFTWGRNITLPCRIKQIINMWQEVGKAMYAPPIRGQIRCSSNITGLLLT
RDGGNGTEIFRPGGGDMRDNWRSELYKYKVVKIE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4laj Heavy Chain-Only IgG2b Llama Antibody Effects Near-Pan HIV-1 Neutralization by Recognizing a CD4-Induced Epitope That Includes Elements of Coreceptor- and CD4-Binding Sites.
Resolution2.14 Å
Binding residue
(original residue number in PDB)		V255 S365 G367 D368 E370 S375 F382 N425 M426 W427 E429 V430 G473
Binding residue
(residue number reindexed from 1)		V139 S227 G229 D230 E232 S237 F244 N270 M271 W272 E274 V275 G315
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:4laj, PDBe:4laj, PDBj:4laj
PDBsum4laj
PubMed23843638
UniProtP35961|ENV_HV1Y2 Envelope glycoprotein gp160 (Gene Name=env)

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