Structure of PDB 4csu Chain F Binding Site BS01

Receptor Information

>4csu Chain F (length=178) Species: 83333 (Escherichia coli K-12)

AKLHDYYKDEVVKKLMTEFNYNSVMQVPRVEKITLNMGVGEAIADKKLLD
NAAADLAAISGQKPLITKARKSVAGFKIRQGYPIGCKVTLRGERMWEFFE
RLITIAVPRIRDFRGLSAKSFDGRGNYSMGVREQIIFPEIDYDKVDRVRG
LDITITTTAKSDEEGRALLAAFDFPFRK

Ligand information

>4csu Chain A (length=115)

gcugcggccguagcgcgguggucccaccugaccccaugccgaacucagaa
gugaaacgccguagcgccgaugguaguguggggucuccccaugcgagagu
agggaacugccaggc

.<<<<<<.....<<<<<<<<....<<<<<<<.............>>>>..
>>>...>>>>>>.>>.<<.....<.<<<<<<<<...>>>>>>>>...>..
.>>...>>>>.>>..

Receptor-Ligand Complex Structure

Structure summary

• PDB: 4csu Structural and Functional Insights Into the Mode of Action of a Universally Conserved Obg Gtpase.
• Resolution: 5.5 Å
• Binding residue (original residue number in PDB): N22 S23 M25 Q26 K32 Q62 K63 P64 L65 T89 R91 W96
• Binding residue (residue number reindexed from 1): N22 S23 M25 Q26 K32 Q62 K63 P64 L65 T89 R91 W96

Gene Ontology

Molecular Function

• GO:0000049 tRNA binding
• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome
• GO:0008097 5S rRNA binding
• GO:0019843 rRNA binding

Biological Process

• GO:0000027 ribosomal large subunit assembly
• GO:0002181 cytoplasmic translation
• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:4csu, PDBe:4csu, PDBj:4csu
• PDBsum: 4csu
• PubMed: 24844575
• UniProt: P62399|RL5_ECOLI Large ribosomal subunit protein uL5 (Gene Name=rplE)