Structure of PDB 4csf Chain F Binding Site BS01
Receptor Information
>4csf Chain F (length=249) Species:
11590
(Toscana virus) [
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ENYRDIALAFLDESADSGTINAWVNEFAYQGFDPKRIVQLVKERGTAKGR
DWKKDVKMMIVLNLVRGNKPEAMMKKMSEKGASIVANLISVYQLKEGNPG
RDTITLSRVSAAFVPWTVQALRVLSESLPVSGTTMDAIAGVTYPRAMMHP
SFAGIIDLDLPNGAGATIADAHGLFMIEFSKTINPSLRTKQANEVAATFE
KPNMAAMSGRFFTREDKKKLLIAVGIIDEDLVLASAVVRSAEKYRAKVG
Ligand information
>4csf Chain a (length=9) [
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uguguuucu
.........
Receptor-Ligand Complex Structure
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PDB
4csf
Structural Insights Into RNA Encapsidation and Helical Assembly of the Toscana Virus Nucleoprotein.
Resolution
2.598 Å
Binding residue
(original residue number in PDB)
K79 T185 I186
Binding residue
(residue number reindexed from 1)
K76 T182 I183
Binding affinity
PDBbind-CN
: Kd=260nM
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003723
RNA binding
Cellular Component
GO:0019013
viral nucleocapsid
GO:0019029
helical viral capsid
GO:0030430
host cell cytoplasm
GO:0042025
host cell nucleus
GO:0044172
host cell endoplasmic reticulum-Golgi intermediate compartment
GO:0044177
host cell Golgi apparatus
GO:1990904
ribonucleoprotein complex
View graph for
Molecular Function
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Cellular Component
External links
PDB
RCSB:4csf
,
PDBe:4csf
,
PDBj:4csf
PDBsum
4csf
PubMed
24688060
UniProt
P21701
|NCAP_TOSV Nucleoprotein (Gene Name=N)
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