Structure of PDB 3vyg Chain F Binding Site BS01

Receptor Information
>3vyg Chain F (length=217) Species: 931 (Thiobacillus thioparus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EVSDFEILEMAVRELAIEKGLFSAEDHRVWKDYVHTLGPLPAARLVAKAW
LDPEYKKLCIEDGVEASKAVGVNWVTSPPTQFGTPSDYCNLRVLADSPTL
KHVVVCTLCSCYPWPILGQSPEWYRSPNYRRRLVRWPRQVLAEFGLQLPS
EVQIRVADSNQKTRYIVMPVRPEGTDGWTEDQLAEIVTRDCLIGVAVPKP
GITVNAKRPVLKANRPV
Ligand information
Ligand ID3CO
InChIInChI=1S/Co/q+3
InChIKeyJAWGVVJVYSANRY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Co+3]
FormulaCo
NameCOBALT (III) ION
ChEMBL
DrugBank
ZINC
PDB chain3vyg Chain F Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3vyg Effects of argnine residue around the substrate pocket on the substrate specificity of thiocyanate hydrolase
Resolution1.72 Å
Binding residue
(original residue number in PDB)		C128 A131 S132 C133
Binding residue
(residue number reindexed from 1)		C106 A109 S110 C111
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) C128 C131 S132 C133
Catalytic site (residue number reindexed from 1) C106 C109 S110 C111
Enzyme Commision number 3.5.5.8: thiocyanate hydrolase.
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0016787 hydrolase activity
GO:0018760 thiocyanate hydrolase activity
GO:0046872 metal ion binding
GO:0046914 transition metal ion binding
Biological Process
GO:0046265 thiocyanate catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3vyg, PDBe:3vyg, PDBj:3vyg
PDBsum3vyg
PubMed
UniProtO66188|SCNC_THITI Thiocyanate hydrolase subunit gamma (Gene Name=scnC)

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