Structure of PDB 3uts Chain F Binding Site BS01
Receptor Information
>3uts Chain F (length=276) Species:
9606
(Homo sapiens) [
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GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWEP
Ligand information
>3uts Chain H (length=10) Species:
9606
(Homo sapiens) [
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ALWGPDPAAA
Receptor-Ligand Complex Structure
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PDB
3uts
Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes.
Resolution
2.712 Å
Binding residue
(original residue number in PDB)
Y7 E63 K66 V67 A69 D77 Y99 T143 K146 L156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 E63 K66 V67 A69 D77 Y99 T143 K146 L156 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:3uts
,
PDBe:3uts
,
PDBj:3uts
PDBsum
3uts
PubMed
22245737
UniProt
P04439
|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)
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