Structure of PDB 3oda Chain F Binding Site BS01

Receptor Information
>3oda Chain F (length=90) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SDKLYRVEYAKSGRASCKKCSESIPKDSLRMAIMVQSPMFDGKVPHWYHF
SCFWKVGHSIRHPDVEVDGFSELRWDDQQKVKKTAEAGGV
Ligand information
Receptor-Ligand Complex Structure
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PDB3oda Crystal Structures of Poly(ADP-ribose) Polymerase-1 (PARP-1) Zinc Fingers Bound to DNA: STRUCTURAL AND FUNCTIONAL INSIGHTS INTO DNA-DEPENDENT PARP-1 ACTIVITY.
Resolution2.64 Å
Binding residue
(original residue number in PDB)
S16 R18 A19 S20 K22 R34
Binding residue
(residue number reindexed from 1)
S12 R14 A15 S16 K18 R30
Enzymatic activity
Enzyme Commision number 2.4.2.-
2.4.2.30: NAD(+) ADP-ribosyltransferase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0008270 zinc ion binding

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Molecular Function
External links
PDB RCSB:3oda, PDBe:3oda, PDBj:3oda
PDBsum3oda
PubMed21233213
UniProtP09874|PARP1_HUMAN Poly [ADP-ribose] polymerase 1 (Gene Name=PARP1)

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