Structure of PDB 3jbq Chain F Binding Site BS01

Receptor Information
>3jbq Chain F (length=328) Species: 9913 (Bos taurus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SHMEETRELQSLAAAVVPSAQTLKITDFSFSDFELSDLETALCTIRMFTD
LNLVQNFQMKHEVLCRWILSVKKNYRKNVAYHNWRHAFNTAQCMFAALKA
GKIQNKLTDLEILALLIAALSHDLDHRGVNNSYIQRSEHPLAQLYCHSIM
EHHHFDQCLMILNSPGNQILSGLSIEEYKTTLKIIKQAILATDLALYIKR
RGEFFELIRKNQFNLEDPHQKELFLAMLMTACDLSAITKPWPIQQRIAEL
VATEFWEQGDLERTVLQQQPIPMMDRNKRDELPKLQVGFIDFVCTQLYEA
LTHVSEDCFPLLDGCRKNRQKWQALAEQ
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3jbq Domain Organization and Conformational Plasticity of the G Protein Effector, PDE6.
Resolution11.0 Å
Binding residue
(original residue number in PDB)		N661 S663 Q666 H678 S679 L725 A726 I729 K730 I802 M804 L816 G819 F820 F823
Binding residue
(residue number reindexed from 1)		N130 S132 Q135 H147 S148 L194 A195 I198 K199 I271 M273 L285 G288 F289 F292
Enzymatic activity
Enzyme Commision number 3.1.4.35: 3',5'-cyclic-GMP phosphodiesterase.
Gene Ontology
Molecular Function
GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0008081 phosphoric diester hydrolase activity
Biological Process
GO:0007165 signal transduction

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Molecular Function
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Biological Process
External links
PDB RCSB:3jbq, PDBe:3jbq, PDBj:3jbq
PDBsum3jbq
PubMed25809480
UniProtP16586;
Q28156

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