Structure of PDB 3hym Chain F Binding Site BS01
Receptor Information
>3hym Chain F (length=301) Species:
9606
(Homo sapiens) [
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ENLDVVVSLAERHYYNCDFKMCYKLTSVVMEKDPFHASCLPVHIGTLVEL
NKANELFYLSHKLVDLYPSNPVSWFAVGCYYLMVGHKNEHARRYLSKATT
LEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPMLYIGLEY
GLTNNSKLAERFFSQALSIAPEDPFVMHEVGVVAFQNGEWKTAEKWFLDA
LEKIKAIGNEVTVDKWEPLLNNLGHVCRKLKKYAEALDYHRQALVLIPQN
ASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFSVTMLGHCIEMYIG
D
Ligand information
>3hym Chain E (length=26) Species:
9606
(Homo sapiens) [
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MLRRKPTRLELKLDDIEEFENIRKDL
Receptor-Ligand Complex Structure
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PDB
3hym
Insights into anaphase promoting complex TPR subdomain assembly from a CDC26-APC6 structure.
Resolution
2.8 Å
Binding residue
(original residue number in PDB)
Y242 Y243 C245 H342 A345 Y357 L369 Y373 L376 E377 D401 F403 H406 E407 E445 N449 N450 R456 K457 N478 S480 Y487 L491 T513 F514 M518 H521
Binding residue
(residue number reindexed from 1)
Y14 Y15 C17 H114 A117 Y129 L141 Y145 L148 E149 D173 F175 H178 E179 E217 N221 N222 R228 K229 N250 S252 Y259 L263 T285 F286 M290 H293
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:3hym
,
PDBe:3hym
,
PDBj:3hym
PDBsum
3hym
PubMed
19668213
UniProt
Q13042
|CDC16_HUMAN Cell division cycle protein 16 homolog (Gene Name=CDC16)
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