Structure of PDB 2zny Chain F Binding Site BS01

Receptor Information
>2zny Chain F (length=146) Species: 53953 (Pyrococcus horikoshii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LDEIDKKIIKILQNDGKAPLREISKITGLAESTIHERIRKLRESGVIKKF
TAIIDPEALGYSMLAFILVKVKAGKYSEVASNLAKYPEIVEVYETTGDYD
MVVKIRTKNSEELNNFLDLIGSIPGVEGTHTMIVLKTHKETTELPI
Ligand information
Ligand IDARG
InChIInChI=1S/C6H14N4O2/c7-4(5(11)12)2-1-3-10-6(8)9/h4H,1-3,7H2,(H,11,12)(H4,8,9,10)/p+1/t4-/m0/s1
InChIKeyODKSFYDXXFIFQN-BYPYZUCNSA-O
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(CC(C(=O)O)N)CNC(=[NH2+])N
CACTVS 3.341N[C@@H](CCCNC(N)=[NH2+])C(O)=O
OpenEye OEToolkits 1.5.0C(C[C@@H](C(=O)O)N)CNC(=[NH2+])N
CACTVS 3.341N[CH](CCCNC(N)=[NH2+])C(O)=O
ACDLabs 10.04O=C(O)C(N)CCCN\C(=[NH2+])N
FormulaC6 H15 N4 O2
NameARGININE
ChEMBL
DrugBank
ZINC
PDB chain2zny Chain F Residue 172 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2zny Interactions between the archaeal transcription repressor FL11 and its coregulators lysine and arginine.
Resolution2.59 Å
Binding residue
(original residue number in PDB)		Y100 E118 T119 T120 G121 D124
Binding residue
(residue number reindexed from 1)		Y76 E94 T95 T96 G97 D100
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0042802 identical protein binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0043200 response to amino acid
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2zny, PDBe:2zny, PDBj:2zny
PDBsum2zny
PubMed19004003
UniProtO59188|REG6_PYRHO HTH-type transcriptional regulator FL11 (Gene Name=fl11)

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