Structure of PDB 2z0j Chain F Binding Site BS01

Receptor Information
>2z0j Chain F (length=237) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRLRVDVIPGEHLAYPDVVLVVDVIRATTTAAAFLEAGAEALYWTPSLES
ALAFKDEDVVLAGETGGLKPPRFDLGNSPREALSAQVAGRVVVMSTTNGT
KAAHAAARTAKHVLLASLYNAHAAARLARELATEEVAILCAGKEGRAGLD
DLYTAGVLAEYLGFLGEVEPEDGARVALAVKRAYPDPLEALSLSAAALAL
KQVGLEADVPFCAQVAKSAAVPVLRGRVGEALIFKRA
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain2z0j Chain F Residue 406 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2z0j Crystal structure of uncharacterized conserved protein from Thermus thermophilus HB8
Resolution1.5 Å
Binding residue
(original residue number in PDB)		D23 I25
Binding residue
(residue number reindexed from 1)		D23 I25
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.3.71: 2-phosphosulfolactate phosphatase.
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0016787 hydrolase activity
GO:0050532 2-phosphosulfolactate phosphatase activity
GO:0050545 sulfopyruvate decarboxylase activity

View graph for
Molecular Function
External links
PDB RCSB:2z0j, PDBe:2z0j, PDBj:2z0j
PDBsum2z0j
PubMed
UniProtQ5SID6|COMB_THET8 Probable 2-phosphosulfolactate phosphatase (Gene Name=comB)

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