Structure of PDB 2va1 Chain F Binding Site BS01

Receptor Information
>2va1 Chain F (length=226) Species: 134821 (Ureaplasma parvum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RKQRIVIKISGACLKQNDSSIIDFIKINDLAEQIEKISKKYIVSIVLGGG
NIWRGSIAKELDMDRNLADNMGMMATIINGLALENALNHLNVNTIVLSAI
KCDKLVHESSANNIKKAIEKEQVMIFVAGTGFPYFTTDSCAAIRAAETES
SIILMGKNGVDGVYDSQFYEHITFNMALTQNLKVMDATALALCQENNINL
LVFNIDKPNAIVDVLEKKNKYTIVSK
Ligand information
Ligand IDPO4
InChIInChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-3
InChIKeyNBIIXXVUZAFLBC-UHFFFAOYSA-K
SMILES
SoftwareSMILES
CACTVS 3.341[O-][P]([O-])([O-])=O
ACDLabs 10.04[O-]P([O-])([O-])=O
OpenEye OEToolkits 1.5.0[O-]P(=O)([O-])[O-]
FormulaO4 P
NamePHOSPHATE ION
ChEMBL
DrugBankDB14523
ZINC
PDB chain2va1 Chain F Residue 1236 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2va1 Structural and Functional Investigations of Ureaplasma Parvum Ump Kinase - a Potential Antibacterial Drug Target
Resolution2.5 Å
Binding residue
(original residue number in PDB)		G12 G49 G50 G51 T138
Binding residue
(residue number reindexed from 1)		G11 G48 G49 G50 T137
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.4.22: UMP kinase.
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0009041 UMP/dUMP kinase activity
GO:0016301 kinase activity
GO:0033862 UMP kinase activity
Biological Process
GO:0006221 pyrimidine nucleotide biosynthetic process
GO:0006225 UDP biosynthetic process
GO:0016310 phosphorylation
GO:0044210 'de novo' CTP biosynthetic process
GO:0046940 nucleoside monophosphate phosphorylation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2va1, PDBe:2va1, PDBj:2va1
PDBsum2va1
PubMed18021254
UniProtQ9PPX6|PYRH_UREPA Uridylate kinase (Gene Name=pyrH)

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