Structure of PDB 2jhh Chain F Binding Site BS01

Receptor Information
>2jhh Chain F (length=209) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SCATGPRNCKDLLDRGYFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQ
RRMDGSVDFYRDWAAYKQGFGSQLGEFWLGNDNIHALTAQGSSELRTDLV
DFEGNHQFAKYKSFKVADEAEKYKLVLGAFVGGSAGNSLTGHNNNFFSTK
DQDNDVSSSNCAEKFQGAWWYADCHASNLNGLYLMGPHESYANGINWSYK
VSEMKVRPA
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain2jhh Chain F Residue 400 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2jhh Structural basis for innate immune sensing by M-ficolin and its control by a pH-dependent conformational switch.
Resolution1.7 Å
Binding residue
(original residue number in PDB)		D233 D235 S237 S239
Binding residue
(residue number reindexed from 1)		D153 D155 S157 S159
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:2jhh, PDBe:2jhh, PDBj:2jhh
PDBsum2jhh
PubMed17897951
UniProtO00602|FCN1_HUMAN Ficolin-1 (Gene Name=FCN1)

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