Structure of PDB 2ian Chain F Binding Site BS01

Receptor Information
>2ian Chain F (length=179) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFA
SFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREP
NVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLP
FLPSTEDVYDCRVEHWGLDEPLLKHWEFD
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2ian Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor
Resolution2.8 Å
Binding residue
(original residue number in PDB)		Q9 A52 S53 F54 E55 N62 N69 I72 K75
Binding residue
(residue number reindexed from 1)		Q7 A50 S51 F52 E53 N60 N67 I70 K73
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process
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Cellular Component
External links
PDB RCSB:2ian, PDBe:2ian, PDBj:2ian
PDBsum2ian
PubMed17334368
UniProtP01903|DRA_HUMAN HLA class II histocompatibility antigen, DR alpha chain (Gene Name=HLA-DRA)

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