Structure of PDB 2ffd Chain F Binding Site BS01
Receptor Information
>2ffd Chain F (length=285) Species:
9606
(Homo sapiens) [
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LQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDITGKDCQDIANK
GAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWI
QYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTST
ADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNG
MQFSTWDNDNDKFEGNCAEQDGSGWWMNKCHAGHLNGVYYQGGTYSKAST
PNGYDNGIIWATWKTRWYSMKKTTMKIIPFNRLTI
Ligand information
>2ffd Chain I (length=4) [
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GPRV
Receptor-Ligand Complex Structure
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PDB
2ffd
The structure of fibrinogen fragment D with the 'A' knob peptide GPRVVE.
Resolution
2.89 Å
Binding residue
(original residue number in PDB)
F295 D301 F322 Q329 D330 K338 C339 H340 Y363 D364
Binding residue
(residue number reindexed from 1)
F186 D192 F213 Q220 D221 K229 C230 H231 Y254 D255
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0005102
signaling receptor binding
Biological Process
GO:0007596
blood coagulation
GO:0030168
platelet activation
GO:0051258
protein polymerization
Cellular Component
GO:0005577
fibrinogen complex
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:2ffd
,
PDBe:2ffd
,
PDBj:2ffd
PDBsum
2ffd
PubMed
16689770
UniProt
P02679
|FIBG_HUMAN Fibrinogen gamma chain (Gene Name=FGG)
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