Structure of PDB 2ajq Chain F Binding Site BS01

Receptor Information
>2ajq Chain F (length=689) Species: 10760 (Escherichia phage T7) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIVSAIAANALLESVTKFHCGVIYDYSTAEYVSYRPSDFGAYLDALEAEV
ARGGLIVFHNGHKYDVPALTKLAKLQLNREFHLPRENCIDTLVLSRLIHS
NLKDTDMGLLRSGKLPGKRFGSHALEAWGYRLGEMKGEYKDDFKRMLEEQ
GEEYVDGMEWWNFNEEMMDYNVQDVVVTKALLEKLLSDKHYFPPEIDFTD
VGYTTFWSESLEAVDIEHRAAWLLAKQERNGFPFDTKAIEELYVELAARR
SELLRKLTETFGSWYQPKGGTEMFCHPRTGKPLPKYPRIKTPKVGGIFKL
DTREYVAGAPYTPVEHVVFNPSSRDHIQKKLQEAGWVPTKYTDKGAPVVD
DEVLEGVRVDDPEKQAAIDLIKEYLMIQKRIGQSAEGDKAWLRYVAEDGK
IHGSVNPNGAVTGRATHAFPNLAQIPGVRSPYGEQCRAAFGAEHHLDGIT
GKPWVQAGIDASGLELRCLAHFMARFDNGEYAHEILNGDIHTKNQIAAEL
PTRDNAKTFIYGFLYGAGDEKIGQIVGAGKERGKELKKKFLENTPAIAAL
RESIQQTLVESSQWVAGEQQVKWKRRWIKGLDGRKVHVRSPHAALNTLLQ
SAGALICKLWIIKTEEMLVEKGLKHGWDGDFAYMAWVHDEIQVGCRTEEI
AQVVIETAQEAMRWVGDHWNFRCLLDTEGKMGPNWAICH
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2ajq Structure of replicative DNA polymerase provides insigts into the mechanisms for processivity, frameshifting and editing
Resolution2.6 Å
Binding residue
(original residue number in PDB)		T357 K359 V363 D365 D366 K394 R429 A438 Q439 P441 G442 H653
Binding residue
(residue number reindexed from 1)		T342 K344 V348 D350 D351 K379 R414 A423 Q424 P426 G427 H638
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
3.1.11.-
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0004527 exonuclease activity
GO:0004529 DNA exonuclease activity
GO:0005515 protein binding
GO:0008408 3'-5' exonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0006302 double-strand break repair
GO:0039693 viral DNA genome replication
GO:0090592 DNA synthesis involved in DNA replication

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Molecular Function
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Biological Process
External links
PDB RCSB:2ajq, PDBe:2ajq, PDBj:2ajq
PDBsum2ajq
PubMed
UniProtP00581|DPOL_BPT7 DNA-directed DNA polymerase (Gene Name=5)

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